Endothelial cell infection in vivo by equine infectious anaemia virus

Equine Infectious Anaemia

Equine infectious anaemia (EIA) is a persistent viral infection of equids. The causative agent, EIA virus (EIAV) is a lentivirus in the family Retroviridae, subfamily Orthoretrovirinae. Other members of the genus Lentivirus include: bovine immunodeficiency virus; caprine arthritis encephalitis virus; feline immunodeficiency virus; human immunodeficiency virus 1; human immunodeficiency virus 2; ...

Chicken infectious anaemia virus infection among broiler chicken flocks in Iran

Chicken infectious anaemia is a viral disease in young chickens which characterized by aplastic anaemia and immunosuppression. Between January 2004 and July 2005, an unusual hemorrhage in subcutaneous and intramuscular tissues of broiler chickens at slaughter houses of Mashhad, Isfahan and Tehran provinces were occurred. Postmortem examination revealed severe hemorrhages in the wings and muscle...

Freedom from equine infectious anaemia virus infection in Spanish Purebred horses

INTRODUCTION No cases of equine infectious anaemia (EIA) have been reported in Spain since 1983. Factors that could increase the risk of reintroducing equine infectious anaemia virus (EIAV) into Spain include the recent occurrence of the disease in Europe and the absence of compulsory serological testing before importation into Spain. AIMS AND OBJECTIVES Given the importance of the Spanish Pu...

Characterisation of Equine Infectious Anaemia Virus (EIAV) strains

Equine endothelial cells support productive infection of equine infectious anemia virus.

Previous cell infectivity studies have demonstrated that the lentivirus equine infectious anemia virus (EIAV) infects tissue macrophages in vivo and in vitro. In addition, some strains of EIAV replicate to high titer in vitro in equine fibroblasts and fibroblast cell lines. Here we report a new cell type, macrovascular endothelial cells, that is infectible with EIAV. We tested the ability of EI...